Acecarbromal

Title: Acecarbromal
CAS Registry Number: 77-66-7
CAS Name: N-[(Acetylamino)carbonyl]-2-bromo-2-ethylbutanamide
Additional Names: N-acetyl-N-bromodiethylacetylurea; acetylbromodiethylacetylcarbamide; N-acetyl-N¢-a-bromo-a-ethylbutyrylcarbamide; acetylcarbromal
Trademarks: Abasin (Bayer); Sedamyl (3M Pharma)
Molecular Formula: C9H15BrN2O3
Molecular Weight: 279.13
Percent Composition: C 38.73%, H 5.42%, Br 28.63%, N 10.04%, O 17.20%
Literature References: Prepn: DE 327129 (1920 to Bayer), Frdl. 13, 809 (1923). HPLC determn in plasma, urine: M. Höbel, G. Bender, Arch. Toxicol. 37, 307 (1977). GC-MS screening procedure in urine: H. H. Maurer, J. Chromatogr. 530, 307 (1990).
Properties: Crystals, slightly bitter taste, mp 108-109°. Slightly sol in water; freely sol in alcohol, ethyl acetate.
Melting point: mp 108-109°
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Acylic Ureides.
Aceclofenac Acedapsone Acediasulfone Acefylline Aceglatone

Acecarbromal
Seletal formula of acebromal
Identifiers
CAS number 77-66-7 YesY
PubChem 6489
ChemSpider 6244 YesY
UNII E47C56IGOY YesY
EC number 201-047-1
KEGG D07059 YesY
MeSH acecarbromal
ChEMBL CHEMBL2104673
Jmol-3D images Image 1
Image 2
Properties
Molecular formula C9H15BrN2O3
Molar mass 279.13 g mol−1
Pharmacology
Routes of
administration
Oral
Legal status


Prescription only

Related compounds
Related compounds
  • Buformin
  • Methylarginine
  • Asymmetric dimethylarginine
  • N-Propyl-L-arginine
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Acecarbromal was discovered by Bayer in 1917.[1] As (Abasin, Carbased, Paxarel, Sedacetyl, Sedanyl), also known as acetyladalin and acetylcarbromal, it was a hypnotic and sedative drug formally sold in the United States and Europe. It is also used in combination with extract of quebracho and vitamin E as a treatment for erectile dysfunction under the brand name Afrodor in Europe.[2][3]