Acetophenazine

Title: Acetophenazine
CAS Registry Number: 2751-68-0
CAS Name: 1-[10-[3-[4-(2-Hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]ethanone
Additional Names: 10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl ketone; 2-acetyl-10-[3-[4-(b-hydroxyethyl)piperazinyl]propyl]phenothiazine; 1-(2-hydroxyethyl)-4-[3-(2-acetyl-10-phenothiazyl)propyl]piperazine
Molecular Formula: C23H29N3O2S
Molecular Weight: 411.56
Percent Composition: C 67.12%, H 7.10%, N 10.21%, O 7.78%, S 7.79%
Literature References: Prepd from 1-(2-hydroxyethyl)piperazine and 10-(3-chloropropyl)-2-acetylphenothiazine: Sherlock, Sperber, US 2985654 (1961 to Schering). Toxicity study: E. W. Schafer, Toxicol. Appl. Pharmacol. 21, 315 (1972).
Derivative Type: Dimaleate
CAS Registry Number: 5714-00-1
Trademarks: Tindal (Schering)
Molecular Formula: C23H29N3O2S.2C4H4O4
Molecular Weight: 643.70
Percent Composition: C 57.84%, H 5.79%, N 6.53%, O 24.86%, S 4.98%
Properties: Crystals from ethanol, mp 167-168.5°. LD50 orally in rats: 433 mg/kg (Schafer).
Melting point: mp 167-168.5°
Toxicity data: LD50 orally in rats: 433 mg/kg (Schafer)
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Phenothiazines.
Acetophenone Acetosulfone Sodium Acetotoluide Acetoxime Acetoxolone

Acetophenazine
Acetophenazine.svg
Systematic (IUPAC) name
1-[10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]-10H-phenothiazin-2-yl]ethanone
Clinical data
MedlinePlus a600010
Legal status  ?
Identifiers
CAS number 2751-68-0 YesY
ATC code N05AB07
PubChem CID 17676
DrugBank DB01063
ChemSpider 16708 YesY
UNII 8620H6K4QH YesY
ChEBI CHEBI:2401 YesY
ChEMBL CHEMBL1085 YesY
Chemical data
Formula C23H29N3O2S 
Mol. mass 411.561 g/mol
 YesY (what is this?)  (verify)

Acetophenazine (Tindal) is a typical antipsychotic of the phenothiazine class.[1]