|Systematic (IUPAC) name|
|Trade names||Melitor, Thymanax, Valdoxan|
|Pregnancy cat.||B1 (AU)|
|Legal status||Prescription Only (S4) (AU) POM (UK)|
|Metabolism||hepatic (90% CYP1A2 and 10% CYP2C9)|
|Excretion||Renal (80%, mostly as metabolites)|
|(what is this?)|
Agomelatine (BAN, rINN; trade names Valdoxan, Melitor, Thymanax) is a melatonergic antidepressant developed by the pharmaceutical company Servier. It is marketed for the treatment of major depressive disorder and has been reported to not produce discontinuation syndrome and have no sexual side effects compared to SSRIs, SNRIs and the older tricyclic antidepressants. Agomelatine may also have positive effects on sleep.