Aldrin

Title: Aldrin
CAS Registry Number: 309-00-2
CAS Name: 1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene
Additional Names: HHDN
Manufacturers' Codes: compd 118
Trademarks: Octalene
Molecular Formula: C12H8Cl6
Molecular Weight: 364.91
Percent Composition: C 39.50%, H 2.21%, Cl 58.29%
Literature References: Chlorinated hydrocarbon insecticide; readily metabolized to dieldrin, q.v. Activity: C. W. Kearns et al., J. Econ. Entomol. 42, 127 (1949). Prepn of aldrin and endo,endo-isomer: Lidov, US 2635977 (1953 to Shell). Alternate syntheses: Schmerling, US 2911447 (1959 to Universal Oil Prod.); Korte, Rechmeier, Ann. 656, 131 (1962). Toxicity study: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969). Review of toxicology and human exposure: Toxicological Profile for Aldrin/Dieldrin (PB2003-100134, 2002) 354 pp.
Properties: Crystals, mp 104°. Vapor pressure at 20°: 7.5´10-5 mm Hg. Very sol in most organic solvents. Practically insol in water. Stable in presence of organic and inorganic alkalies; stable to the action of hydrated metal chlorides. LD50 in male, female rats (mg/kg): 39, 60 orally (Gaines).
Melting point: mp 104°
Toxicity data: LD50 in male, female rats (mg/kg): 39, 60 orally (Gaines)
Derivative Type: endo,endo-Isomer
Additional Names: Isodrin
Manufacturers' Codes: compd 711
Properties: Crystals, mp 240-242°. LD50 in male, female rats (mg/kg): 15, 7.0 orally (Gaines).
Melting point: mp 240-242°
Toxicity data: LD50 in male, female rats (mg/kg): 15, 7.0 orally (Gaines)
CAUTION: Potential symptoms of overexposure by ingestion, inhalation, or skin absorption are headache, dizziness; nausea, vomitting, malaise; myoclinic limb jerks; clonic and tonic convulsions; coma; hematuria, azotemia. Potential occupational carcinogen. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 2003) p 8; Patty's Industrial Hygiene and Toxicology vol. 2B, G. D. Clayton, F. E. Clayton, Eds. (Wiley-Interscience, New York, 4th ed., 1994) pp 1517-1523.
Use: Formerly as insecticide.
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Aldrin
Aldrin
Aldrin-from-xtal-3D-balls.png
Identifiers
CAS number 309-00-2 YesY
ChemSpider 10292747 YesY
UNII OZE3CLY605 YesY
KEGG C07552 YesY
Jmol-3D images Image 1
Properties
Molecular formula C12H8Cl6
Molar mass 364.91 g mol−1
Appearance colorless solid
Melting point 104 °C; 219 °F; 377 K
Solubility in water slightly soluble
Vapor pressure 7.5 × 10−5 mmHg @ 20 °C
Hazards
NFPA 704
NFPA 704.svg
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Flash point 66 °C; 151 °F; 339 K
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Aldrin is an organochlorine insecticide that was widely used until the 1970s, when it was banned in most countries. It is a colourless solid. Before the ban, it was heavily used as a pesticide to treat seed and soil. Aldrin and related "cyclodiene" pesticides became notorious as persistent organic pollutants.[1]