Alstonidine

Title: Alstonidine
CAS Registry Number: 25394-75-6
CAS Name: 3b-(Hydroxymethyl)-2a-methyl-4b-[(9-methyl-9H-pyrido[3,4-b]indol-1-yl)methyl]-2H-pyran-5-carboxylic acid methyl ester
Molecular Formula: C22H24N2O4
Molecular Weight: 380.44
Percent Composition: C 69.46%, H 6.36%, N 7.36%, O 16.82%
Literature References: From the bark or root of Alstonia constricta F. Muell., Apocynaceae: Hesse, Ann. 205, 360 (1880); Svoboda, J. Am. Pharm. Assoc. 46, 508 (1957). Structure: Boaz et al., ibid. 510. Stereochemistry: Crow et al., Aust. J. Chem. 23, 2489 (1970).
Properties: Fine crystals from ether, mp 188-190°. Practically insol in water. Sol in alcohol, chloroform, ether, acetone, 5% HCl. uv max (methanol): 238, 291, 360 nm (log e 4.66, 4.25, 3.74). The acid solutions are fluorescent.
Melting point: mp 188-190°
Absorption maximum: uv max (methanol): 238, 291, 360 nm (log e 4.66, 4.25, 3.74)
Derivative Type: Acetyl deriv trihydrate
Molecular Formula: C24H26N2O5.3H2O
Molecular Weight: 476.52
Percent Composition: C 60.49%, H 6.77%, N 5.88%, O 26.86%
Properties: Fine needles from dil acetone, mp 92-96°.
Melting point: mp 92-96°
Alstonine Althea Althiazide Altretamine Aluminon