Ambucaine

Title: Ambucaine
CAS Registry Number: 119-29-9
CAS Name: 4-Amino-2-butoxybenzoic acid 2-diethylaminoethyl ester
Additional Names: 2-butoxy-4-aminobenzoic acid b-diethylaminoethyl ester; b-diethylaminoethyl 2-butoxy-4-aminobenzoate; 2-diethylaminoethyl 4-amino-2-n-butoxybenzoate; ambutoxate
Molecular Formula: C17H28N2O3
Molecular Weight: 308.42
Percent Composition: C 66.20%, H 9.15%, N 9.08%, O 15.56%
Literature References: Prepn: Büchi et al., Helv. Chim. Acta 34, 1002 (1951); Clinton et al., J. Am. Chem. Soc. 74, 592 (1952); Clinton, Laskowski, US 2689248 (1954 to Sterling Drug); Grimme, Schmitz, Ber. 87, 179 (1954).
Derivative Type: Hydrochloride
CAS Registry Number: 5870-25-7
Manufacturers' Codes: Win-3706
Trademarks: Sympocaine (Winthrop)
Molecular Formula: C17H28N2O3.HCl
Molecular Weight: 344.88
Percent Composition: C 59.20%, H 8.48%, N 8.12%, O 13.92%, Cl 10.28%
Properties: Crystals, mp 127°.
Melting point: mp 127°
Derivative Type: Dihydrochloride
Properties: Crystals, decomp 156.8-159°.
Therap-Cat: Anesthetic (local).
Keywords: Anesthetic (Local).
Status: This monograph has been retired and is no longer subject to revision or update.
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