Ambucetamide

Title: Ambucetamide
CAS Registry Number: 519-88-0
CAS Name: a-(Dibutylamino)-4-methoxybenzeneacetamide
Additional Names: a-dibutylamino-a-(p-methoxyphenyl)acetamide; a-p-methoxyphenyl-a-di-n-butylaminoacetamide
Manufacturers' Codes: A-16
Molecular Formula: C17H28N2O2
Molecular Weight: 292.42
Percent Composition: C 69.82%, H 9.65%, N 9.58%, O 10.94%
Literature References: Antispasmodic. Prepn starting with dibutylamine, anisaldehyde and potassium cyanide: Janssen, J. Am. Chem. Soc. 76, 6192 (1954).
Properties: Rods from ethanol + 10% ether. mp 134° (first reported as mp 125-127°). Practically insol in water. Sol in ethanol, isopropanol, glacial acetic acid.
Melting point: mp 134°; first reported as mp 125-127°
Status: This monograph has been retired and is no longer subject to revision or update.
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Ambucetamide
Ambucetamide.svg
Systematic (IUPAC) name
2-(dibutylamino)-2-(4-methoxyphenyl)acetamide
Clinical data
Legal status  ?
Identifiers
CAS number 519-88-0
ATC code None
PubChem CID 10616
ChemSpider 10171 YesY
UNII 131B408RZI YesY
ChEMBL CHEMBL2104638
Chemical data
Formula C17H28N2O2 
Mol. mass 292.417 g·mol−1
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Ambucetamide is an antispasmodic found to be particularly effective for the relief of menstrual pain. It was discovered in 1953 by Paul Janssen.