Amixetrine

Title: Amixetrine
CAS Registry Number: 24622-72-8
CAS Name: 1-[2-(3-Methylbutoxy)-2-phenylethyl]pyrrolidine
Additional Names: 1-[b-(isopentyloxy)phenethyl]pyrrolidine; N-(2-phenyl-2-isoamyloxy)ethylpyrrolidine
Molecular Formula: C17H27NO
Molecular Weight: 261.40
Percent Composition: C 78.11%, H 10.41%, N 5.36%, O 6.12%
Literature References: Prepn by reacting styrene and isoamyl alcohol with t-butyl hypobromite and then condensing the product with pyrrolidine: Mauvernay, Busch, DE 1811767 (1969 to C.E.R.M.), C.A. 72, 21607e (1970). Identification of urinary metabolites in humans and dogs: M. Constantin et al., Arzneim.-Forsch. 26, 80 (1976). Pharmcokinetics: M. Constantin, J. F. Pognat, ibid. 28, 646 (1978).
Properties: bp2 121°. nD21.6 1.4978.
Boiling point: bp2 121°
Index of refraction: nD21.6 1.4978
Derivative Type: Hydrochloride
CAS Registry Number: 24622-52-4
Trademarks: Somagest (Riom)
Molecular Formula: C17H27NO.HCl
Molecular Weight: 297.86
Percent Composition: C 68.55%, H 9.48%, N 4.70%, O 5.37%, Cl 11.90%
Properties: Crystals, mp 150°.
Melting point: mp 150°
Therap-Cat: Antispasmodic.
Status: This monograph has been retired and is no longer subject to revision or update.
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Amixetrine
Amixetrine.png
Systematic (IUPAC) name
1-[2-(3-methylbutoxy)-2-phenylethyl]pyrrolidine
Clinical data
Legal status Prescription only
Routes Oral
Identifiers
CAS number 24622-72-8
ATC code None
PubChem CID 71911
ChemSpider 64922 YesY
UNII 7UL287YTPJ YesY
Chemical data
Formula C17H27NO 
Mol. mass 261.40 g/mol
 YesY (what is this?)  (verify)

Amixetrine (Somagest) is a drug that is no longer marketed.[1] According to various sources it has been said to be an antidepressant, antispasmodic, anti-inflammatory, anticholinergic, antihistamine, and antiserotonergic, but its actual indications and pharmacology are unclear.[1][2]