Amoproxan

Title: Amoproxan
CAS Registry Number: 22661-76-3
CAS Name: 3,4,5-Trimethoxybenzoic acid 1-[(3-methylbutoxy)methyl]-2-(4-morpholinyl)ethyl ester
Additional Names: 3,4,5-trimethoxybenzoic acid 1-[(isopentyloxy)methyl]-2-morpholinoethyl ester; a-[(isopentyloxy)methyl]-4-morpholineethanol 3,4,5-trimethoxybenzoate; 4-[3-(isoamyloxy)-2-(3,4,5-trimethoxybenzoyloxy)propyl]tetrahydro-1,4-oxazine; 3,4,5-trimethoxybenzoic acid 2-(isopentyloxy)-1-(morpholinomethyl)ethyl ester
Molecular Formula: C22H35NO7
Molecular Weight: 425.52
Percent Composition: C 62.10%, H 8.29%, N 3.29%, O 26.32%
Literature References: Prepn: Mauvernay et al., GB 1211307 corresp to US 3781432 (1970, 1973 to C.E.R.M.) and US 3790569 (1974). Pharmacology: Duchene-Marullaz et al., Therapie 24, 665 (1969); Pernod et al., ibid. 675; Roulet et al., ibid. 27, 93 (1972).
Derivative Type: Hydrochloride
CAS Registry Number: 22661-96-7
Manufacturers' Codes: CERM-730
Molecular Formula: C22H35NO7.HCl
Molecular Weight: 461.98
Percent Composition: C 57.20%, H 7.85%, N 3.03%, O 24.24%, Cl 7.67%
Properties: Crystals from anhydr isopropyl alcohol, mp 145°. Sol in water, alcohol; very slightly sol in ethyl acetate.
Melting point: mp 145°
Therap-Cat: Antiarrhythmic.
Keywords: Antiarrhythmic.
Status: This monograph has been retired and is no longer subject to revision or update.
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