Amprotropine Phosphate

Title: Amprotropine Phosphate
CAS Registry Number: 134-53-2
CAS Name: a-(Hydroxymethyl)benzeneacetic acid 3-(diethylamino)-2,2-dimethylpropyl ester phosphate (1:1) salt
Additional Names: 3-diethylamino-2,2-dimethylpropyl tropate phosphate
Trademarks: Syntropan (Roche)
Molecular Formula: C18H32NO7P
Molecular Weight: 405.42
Percent Composition: C 53.33%, H 7.96%, N 3.45%, O 27.62%, P 7.64%
Literature References: Anticholinergic. Prepn: US 1932341 (1933); US 1987546 (1935).
Properties: Bitter crystals, mp 142-145°. Freely sol in water; slightly sol in abs alcohol. Insol in chloroform, ether. The aq soln is acid to litmus.
Melting point: mp 142-145°
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic.
Status: This monograph has been retired and is no longer subject to revision or update.
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