Arginine Glutamate

Title: Arginine Glutamate
CAS Registry Number: 4320-30-3
CAS Name: L-Glutamic acid compd with L-arginine
Trademarks: Modumate (Abbott)
Molecular Formula: C11H23N5O6
Molecular Weight: 321.33
Percent Composition: C 41.12%, H 7.21%, N 21.79%, O 29.87%
Literature References: Prepd from L-arginine and L-glutamic acid: Barker, Chang, US 2851482 (1958 to General Mills). Activity studies: Weisburger et al., Toxicol. Appl. Pharmacol. 14, 163 (1969); Yamamoto, Weisburger, Life Sci. 9(II), 285 (1970). Crystal and molecular structure: T. N. Bhat, M. Vijayan, Acta Crystallogr. B33, 1754 (1977). Reduction of blood ammonia: L. Zieve et al., Metab. Brain Dis. 4, 113 (1989).
Properties: Crystals, dec 193-194.5°. Supplied as a 25% (w/v) soln in water for injection; each 100 ml represents 13.5 g of arginine and 11.5 g of glutamic acid.
Therap-Cat: Ammonia detoxicant (hepatic failure).
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