Title: Azosemide
CAS Registry Number: 27589-33-9
CAS Name: 2-Chloro-5-(1H-tetrazol-5-yl)-4-[(2-thienylmethyl)amino]benzenesulfonamide
Additional Names: 2-chloro-5-(2H-tetrazol-5-yl)-N4-2-thenylsulfanilamide; 5-(4¢-chloro-2¢-thenylamino-5¢-sulfamoylphenyl)tetrazole
Manufacturers' Codes: Ple-1053
Trademarks: Diart (Boehringer, Mann.); Luret (Sanofi Winthrop)
Molecular Formula: C12H11ClN6O2S2
Molecular Weight: 370.84
Percent Composition: C 38.87%, H 2.99%, Cl 9.56%, N 22.66%, O 8.63%, S 17.29%
Literature References: Prepn: A. Popelak et al., DE 1815922; eidem, US 3665002 (1968, 1972 both to Boehringer, Mann.). Separation and analysis in blood and urine by HPLC: R. Seiwell, C. Brater, J. Chromatogr. 182, 257 (1980). Sites of action: C. Brater, Clin. Pharmacol. Ther. 25, 428 (1979). Clinical and pharmacological studies: F. Krueck et al., Eur. J. Clin. Pharmacol. 14, 153 (1978). Diuretic effect in animals: J. Greven, O. Heidenreich, Arzneim.-Forsch. 31, 346, 350 (1981).
Properties: Crystals, mp 218-221°.
Melting point: mp 218-221°
Therap-Cat: Diuretic.
Keywords: Diuretic; Sulfonamide Derivatives.
Azoxybenzene Azoxystrobin Aztreonam Azulene Azure B

Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
Legal status  ?
CAS number 27589-33-9 N
ATC code None
PubChem CID 2273
ChemSpider 2186 YesY
KEGG D01323 YesY
ChEBI CHEBI:31248 YesY
Chemical data
Formula C12H11ClN6O2S2 
Mol. mass 370.84 g/mol
 N (what is this?)  (verify)

Azosemide is a high-ceiling diuretic agent.