Literature References: An abbreviation for Bacillus Calmette-Guérin, a strain of Mycobacterium tuberculosis. Prepn of BCG labeled with C14: Pasquier, Kurylowicz, Rev. Immunol. 20, 245 (1956). Has the potential to act as a non-specific immunopotentiating agent that stimulates the whole range of immune responses. Role as an immunotherapeutic agent: Bartlett and Zbar et al., J. Natl. Cancer Inst. 48, 245, 1441, 1709 (1972); 49, 119 (1972). Comparison of potentiation of specific tumor immunity in mice: M. T. Scott, R. Bomford, ibid. 57, 555 (1976). Review of use in Hodgkin's disease: H. Zywicka-Lopaciuk et al., Arch. Immunol. Ther. Exp. 29, 739-755 (1981); in operable lung cancer: B. H. Stack et al., Thorax 37, 588-593 (1982). Review of use as anti-tumor agent and of the interaction of BCG with cells of the mammalian immune system: M. Davies, Biochim. Biophys. Acta 651, 143-174 (1982). Review of pathogenesis of tuberculosis and the effectiveness of BCG vaccination: H. G. ten Dam, A. Pio, Tubercle 63, 225-233 (1982).
Therap-Cat: BCG vaccine as active immunizing agent.
Therap-Cat-Vet: Vaccination vs. tuberculosis (cattle). Use prohibited where bovine tuberculosis eradication programs are in progress.