|Bakankosin||Balofloxacin||Balsalazide||Balsam Canada||Balsam Gurjun|
|Jmol-3D images||Image 1|
|Molar mass||270.24 g mol−1|
(what is: / ?)|
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Baicalein (5,6,7-trihydroxyflavone) is a flavone, a type of flavonoid, originally isolated from the roots of Scutellaria baicalensis. It is also reported in Oroxylum indicum or Indian trumpetflower. It is the aglycone of baicalin.
The flavonoid has been shown to inhibit certain types of lipoxygenases and act as an anti-inflammatory agent.It has antiproliferative effects on ET-1-induced proliferation of pulmonary artery smooth muscle cell proliferation via inhibition of TRPC1 channel expression. Possible antidepressant effects have also been attributed to baicalein in animal research.
Baicalein is an inhibitor of CYP2C9, an enzyme of the cytochrome P450 system that metabolizes drugs in the body.
A derivative of baicalin is a known prolyl endopeptidase inhibitor.
It is one of the active ingredients of Sho-Saiko-To, a Japanese herbal supplement believed to enhance liver health.