Bamifylline

Title: Bamifylline
CAS Registry Number: 2016-63-9
CAS Name: 7-[2-[Ethyl(2-hydroxyethyl)amino]ethyl]-3,7-dihydro-1,3-dimethyl-8-(phenylmethyl)-1H-purine-2,6-dione
Additional Names: 8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]theophylline; 8-benzyl-7-[N-ethyl-N-(b-hydroxyethyl)aminoethyl]theophylline; benzetamophylline; bamiphylline
Manufacturers' Codes: 8102 CB
Molecular Formula: C20H27N5O3
Molecular Weight: 385.46
Percent Composition: C 62.32%, H 7.06%, N 18.17%, O 12.45%
Literature References: Prepn: BE 602888 (1961 to Christiaens), C.A. 56, 5981c (1962). Pharmacology: Georges et al., Therapie 17, 211 (1962). Metabolism: Dodion et al., Arzneim.-Forsch. 19, 785 (1969). Toxicological studies: Georges et al., ibid. 18, 460 (1968).
Properties: Crystals, mp 80-80.5°.
Melting point: mp 80-80.5°
Derivative Type: Hydrochloride
CAS Registry Number: 20684-06-4
Manufacturers' Codes: AC-3810; BAX-2739Z
Trademarks: Briofil (Alfa); Trentadil (Evans)
Molecular Formula: C20H27N5O3.HCl
Molecular Weight: 421.92
Percent Composition: C 56.93%, H 6.69%, N 16.60%, O 11.38%, Cl 8.40%
Properties: Crystals, mp 185-186°. LD50 in mice, rats (mg/kg): 246, 1139 orally; 89, 131 i.p.; 67, 65 i.v. (Georges).
Melting point: mp 185-186°
Toxicity data: LD50 in mice, rats (mg/kg): 246, 1139 orally; 89, 131 i.p.; 67, 65 i.v. (Georges)
Therap-Cat: Bronchodilator.
Keywords: Bronchodilator; Xanthine Derivatives.
Bamipine Baptigenin Baptisia Barban Barbasco

Bamifylline
Bamifylline.png
Identifiers
CAS number 2016-63-9 N
PubChem 16229
ChemSpider 15401 YesY
UNII ZTY15D026H YesY
ATC code R03DA08
Jmol-3D images Image 1
Properties
Molecular formula C20H27N5O3
Molar mass 385.46008
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist.[1][2]