Belladonnine

Title: Belladonnine
CAS Registry Number: 510-25-8
CAS Name: 1,2,3,4-Tetrahydro-1-phenyl-1,4-naphthalenedicarboxylic acid bis(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) ester
Additional Names: isatropylditropeine; tropyl isatropate; ditropyl isatropate
Molecular Formula: C34H42N2O4
Molecular Weight: 542.71
Percent Composition: C 75.25%, H 7.80%, N 5.16%, O 11.79%
Literature References: From Atropa belladonna L. and allied Solanaceae. Probably formed during the process of extraction. Upon hydrolysis the substance extracted from plants yields b-isatropic acid and tropine: Küssner, Arch. Pharm. 276, 617 (1938); Hotovy et al., US 2734062 (1956 to E. Merck).
Properties: Crystals from ethyl acetate, mp 129°. Sparingly sol in water, petr ether. Sol in alcohol, benzene, chloroform, ethyl acetate.
Melting point: mp 129°
Derivative Type: Bisulfate monohydrate
CAS Registry Number: 5908-89-4
Trademarks: Bellacristin
Molecular Formula: C34H42N2O4.H2SO4.H2O
Molecular Weight: 658.80
Percent Composition: C 61.99%, H 7.04%, N 4.25%, O 21.86%, S 4.87%
Properties: Crystals, sol in water.
Derivative Type: Bis[ethobromide] tetrahydrate
Additional Names: Belladonnine bis[bromoethylate] tetrahydrate
Manufacturers' Codes: C-100
Molecular Formula: C38H52Br2N2O4.4H2O
Molecular Weight: 832.70
Percent Composition: C 54.81%, H 7.26%, Br 19.19%, N 3.36%, O 15.37%
Properties: A quaternary tetrahydrate salt, crystals from water + acetone, mp 98-101°. uv max: 258, 261 nm. E1%1cm 4.8. Sol in water, methanol, ethanol. Practically insol in ether, petr ether, benzene, ethyl acetate.
Melting point: mp 98-101°
Absorption maximum: uv max: 258, 261 nm
Status: This monograph has been retired and is no longer subject to revision or update.
Bemegride Bemotrizinol Benactyzine Benalaxyl Benapryzine