Bencyclane

Title: Bencyclane
CAS Registry Number: 2179-37-5
CAS Name: N,N-Dimethyl-3-[[1-(phenylmethyl)cycloheptyl]oxy]-1-propanamine
Additional Names: 3-[(1-benzylcycloheptyl)oxy]-N,N-dimethylpropylamine; 1-benzyl-1-(3-dimethylaminopropoxy)cycloheptane; N-[3-(1-benzylcycloheptyloxy)propyl]-N,N-dimethylamine; benzcyclan
Molecular Formula: C19H31NO
Molecular Weight: 289.46
Percent Composition: C 78.84%, H 10.79%, N 4.84%, O 5.53%
Literature References: Prepn: Pallos et al., HU 151865 (1965 to EGYT), C.A. 62, 16125b (1965). Series of articles on pharmacology: Arzneim.-Forsch. 20, 1337-1460 (1970). Toxicity: E. Komlos, L. E. Petöcz, ibid. 1338.
Properties: bp3 146-156°.
Boiling point: bp3 146-156°
Derivative Type: Fumarate
CAS Registry Number: 14286-84-1
Manufacturers' Codes: EGYT-201
Trademarks: Angiociclan (Organon); Dantrium (Bago); Dilangio (Fournier); Fludilat (Thiemann); Fluxema (Italfarmaco); Halidor (Sumitomo); Vasorelax (Farmasa)
Molecular Formula: C19H31NO.C4H4O4
Molecular Weight: 405.53
Percent Composition: C 68.12%, H 8.70%, N 3.45%, O 19.73%
Properties: Crystals from 25% ethanol, mp 131-133°. Soly in water at 25°: 1 g/100 ml; in hot water: 2 g/100 ml. Poorly sol in acetone, easily in alc. uv spectrum: Simonyi et al., Acta Pharm. Hung. 36, 257 (1966). At pH 3.4-6.6, uv max (ethanol): 207 nm. LD50 in mice, rats (mg/kg): 445.6, 414 orally; 49.9, 41.3 i.v.; 132, 86.3 i.p.; 203, 257 s.c. (Komlos, Petöcz).
Melting point: mp 131-133°
Absorption maximum: uv max (ethanol): 207 nm
Toxicity data: LD50 in mice, rats (mg/kg): 445.6, 414 orally; 49.9, 41.3 i.v.; 132, 86.3 i.p.; 203, 257 s.c. (Komlos, Petöcz)
Therap-Cat: Vasodilator (peripheral, cerebral).
Keywords: Calcium Channel Blocker; Vasodilator (Cerebral); Vasodilator (Peripheral).
Bendamustine Bendazac Bendazol Bendiocarb Bendroflumethiazide

Bencyclane
Bencyclane.png
Identifiers
CAS number 2179-37-5 N
PubChem 2312
ChemSpider 2222 YesY
ATC code C04AX11
Jmol-3D images Image 1
Properties
Molecular formula C19H31NO
Molar mass 289.46 g mol−1
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Bencyclane is a calcium channel blocker.