CAS Registry Number: 98730-04-2
CAS Name: 4-(Dichloroacetyl)-3,4-dihydro-3-methyl-2H-1,4-benzoxazine
Manufacturers' Codes: CGA-154281
Molecular Formula: C11H11Cl2NO2
Molecular Weight: 260.12
Percent Composition: C 50.79%, H 4.26%, Cl 27.26%, N 5.38%, O 12.30%
Literature References: Protects maize from toxic effects of chloroacetanilide herbicides. Increases the expression of glutathione S-transferase (GST) isozymes in plants, accelerating herbicide metabolism. Prepn: H. Moser, EP 149974; idem, US 4618361 (1985, 1986 both to Ciba-Geigy). Effects on metolachlor, q.v., metabolism in corn: C. K. Cottingham, K. K. Hatzios, Z. Naturforsch. 46c, 846 (1991). Efficacy and mode of action studies: L. Rowe et al., Weed Sci. 39, 78 (1991); E. P. Fuerst et al., Pestic. Sci. 43, 242 (1995). Metabolism studies: K. D. Miller et al., J. Agric. Food Chem. 44, 3326, 3335 (1996). Environmental tolerances: Fed. Regist. 63, 7299 (1998).
Properties: Crystals from diisopropyl ether, mp 105-107°. LD50 (mg/kg): >5000 orally in rats; >2010 dermally in rabbits. LC50 in rats (mg/l): >2000 by inhalation (Fed. Regist.).
Melting point: mp 105-107°
Toxicity data: LD50 (mg/kg): >5000 orally in rats; >2010 dermally in rabbits; LC50 in rats (mg/l): >2000 by inhalation (Fed. Regist.)
Use: Herbicide safener.