Benzoxonium Chloride

Title: Benzoxonium Chloride
CAS Registry Number: 19379-90-9
CAS Name: N-Dodecyl-N,N-bis(2-hydroxyethyl)benzenemethanaminium chloride
Additional Names: benzyldodecylbis(2-hydroxyethyl)ammonium chloride; dodecyldi(b-hydroxyethyl)benzylammonium chloride
Manufacturers' Codes: D-301; ZY-15021
Trademarks: Absonal (Boehringer, Ing.); Bactofen (HMR); Bialcol (Novartis)
Molecular Formula: C23H42ClNO2
Molecular Weight: 400.04
Percent Composition: C 69.05%, H 10.58%, Cl 8.86%, N 3.50%, O 8.00%
Literature References: Quaternary ammonium salt with antimicrobial activity. Prepn: CH 306648 (1955 to Ciba), C.A. 51, 2023g (1957). Antimicrobial activity and toxicology: H. Goeth et al., Arzneim.-Forsch. 9, 622 (1959). Potentiometric determn: S. Pinzauti, E. La Porta, Analyst 102, 938 (1977). Clinical evaluation in dental plaque control: U. P. Saxer et al., J. Clin. Periodontol. 9, 162 (1982). In vitro antibacterial spectrum: M. Cortat, P. Fels, Arzneim.-Forsch. 37, 463 (1987). Clinical evaluation in pharyngeal infections: M. A. Weibel et al., ibid. 467.
Properties: Colorless powder from ethyl ether, mp 107-109°. Sol in water, alcohol, benzene, toluene, chlorobenzene. LD50 orally in rats: 750 mg/kg (Goeth).
Melting point: mp 107-109°
Toxicity data: LD50 orally in rats: 750 mg/kg (Goeth)
Therap-Cat: Antiseptic.
Therap-Cat-Vet: Antiseptic.
Keywords: Antiseptic/Disinfectant; Quaternary Ammonium Compounds.
Benzoyl Chloride Benzoyl Isothiocyanate Benzoylecgonine Benzoylpas Benzphetamine