Bermoprofen

Title: Bermoprofen
CAS Registry Number: 78499-27-1
CAS Name: 10,11-Dihydro-a,8-dimethyl-11-oxodibenz[b,f]oxepin-2-acetic acid
Additional Names: 2-(8-methyl-10,11-dihydro-11-oxodibenz[b,f]oxepin-2-yl)propionic acid
Manufacturers' Codes: AD-1590; AJ-1590
Trademarks: Dibenon (Dainippon)
Molecular Formula: C18H16O4
Molecular Weight: 296.32
Percent Composition: C 72.96%, H 5.44%, O 21.60%
Literature References: Prostaglandin synthetase inhibitor. Prepn: H. Uno et al., EP 3893; eidem, US 4238620 (1979, 1980 both to Dainippon); Y. Nagai et al., J. Med. Chem. 25, 1065 (1982). Pharmacology: H. Nakamura et al., Arzneim.-Forsch. 33, 1555 (1983). Mechanism of action: K. Ishii et al., Yakugaku Zasshi 108, 1001 (1988), C.A. 110, 33462v (1989).
Properties: Crystals from toluene, mp 128-129°. LD50 in mice, rats (mg/kg): 500, 147 orally (Nakamura).
Melting point: mp 128-129°
Toxicity data: LD50 in mice, rats (mg/kg): 500, 147 orally (Nakamura)
Therap-Cat: Anti-inflammatory; analgesic; antipyretic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Arylpropionic Acid Derivatives; Antipyretic.
Berninamycin Beryllium Acetate Beryllium Acetylacetonate Beryllium Borohydride Beryllium Bromide