Bromodiphenhydramine

Title: Bromodiphenhydramine
CAS Registry Number: 118-23-0
CAS Name: 2-[(4-Bromophenyl)phenylmethoxy]-N,N-dimethylethanamine
Additional Names: 2-(p-bromo-a-phenylbenzyloxy)-N,N-dimethylethylamine; b-(p-bromobenzhydryloxy)ethyldimethylamine; b-dimethylaminoethyl p-bromobenzhydryl ether; bromdiphenhydramine; bromazine; bromanautine
Trademarks: Bromo-Benadryl; Deserol; Histabromamine
Molecular Formula: C17H20BrNO
Molecular Weight: 334.25
Percent Composition: C 61.09%, H 6.03%, Br 23.91%, N 4.19%, O 4.79%
Literature References: Prepn: Rieveschl, US 2527963 (1950 to Parke, Davis).
Derivative Type: Hydrochloride
CAS Registry Number: 1808-12-4
Trademarks: Ambodryl (Parke-Davis)
Molecular Formula: C17H20BrNO.HCl
Molecular Weight: 370.71
Percent Composition: C 55.08%, H 5.71%, Br 21.55%, N 3.78%, O 4.32%, Cl 9.56%
Properties: Crystals from isopropanol, mp 144-145°.
Melting point: mp 144-145°
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Aminoalkylethers.
Bromofenofos Bromoform Bromolysergide Bromophenol Bromophos

Bromazine
Bromazine.svg
Systematic (IUPAC) name
2-[(4-bromophenyl)-phenylmethoxy]-N,N-dimethylethanamine
Clinical data
MedlinePlus a682065
Legal status  ?
Routes Oral
Pharmacokinetic data
Bioavailability High
Protein binding 96%
Metabolism Mostly hepatic (CYP-mediated), also renal
Half-life 1 to 4 hours
Identifiers
CAS number 1808-12-4 YesY 1808-12-4
ATC code R06AA01
PubChem CID 2444
DrugBank DB01237
ChemSpider 2350 YesY
UNII 202J683U97 YesY
ChEBI CHEBI:59177 YesY
ChEMBL CHEMBL1201245 N
Chemical data
Formula C17H20BrNO 
Mol. mass 334.251 g/mol
 N (what is this?)  (verify)

Bromazine (trade names Ambrodyl, Ambrodil and others), also known as bromodiphenhydramine, is an antihistamine and anticholinergic.[1] It is a halogenated form of diphenhydramine and in many respects is somewhat stronger than the parent compound.