Title: Bucolome
CAS Registry Number: 841-73-6
CAS Name: 5-Butyl-1-cyclohexyl-2,4,6(1H,3H,5H)pyrimidinetrione
Additional Names: 5-butyl-1-cyclohexylbarbituric acid; 5-n-butyl-1-cyclohexyl-2,4,6-trioxoperhydropyrimidine; BCP
Trademarks: Paramidin (Takeda)
Molecular Formula: C14H22N2O3
Molecular Weight: 266.34
Percent Composition: C 63.13%, H 8.33%, N 10.52%, O 18.02%
Literature References: Prepn: Senda et al., US 3243344 and US 3274195 (both 1966 to Takeda). Metabolic studies in man: Yashiki et al., Chem. Pharm. Bull. 19, 468, 869 (1971).
Properties: Needles from methanol, mp 84°. bp0.8 185-187°.
Melting point: mp 84°
Boiling point: bp0.8 185-187°
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal).
Bucumolol Budipine Budralazine Bufalin Bufencarb

Systematic (IUPAC) name
Clinical data
AHFS/Drugs.com International Drug Names
Legal status  ?
CAS number 841-73-6
ATC code None
PubChem CID 2461
ChemSpider 2367 YesY
UNII 9T08RAL174 YesY
ChEBI CHEBI:31314 YesY
Synonyms Bucolome, Paramidine
Chemical data
Formula C14H22N2O3 
Mol. mass 224.256 g/mol
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Bucolome (Paramidine) is a barbiturate derivative. Unlike most barbiturates it does not have any significant sedative or hypnotic effects, but instead acts as an analgesic and antiinflammatory. It also acts as a CYP2C9 inhibitor and reduces the metabolism of several commonly used drugs, which makes it useful for potentiating or extending the duration of action of those drugs, or reducing the production of unwanted metabolites.[1][2][3]