Title: Butethal
CAS Registry Number: 77-28-1
CAS Name: 5-Butyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
Additional Names: 5-butyl-5-ethylbarbituric acid; butobarbitone
Trademarks: Soneryl (M & B); Neonal (Abbott); Butobarbital; Etoval
Molecular Formula: C10H16N2O3
Molecular Weight: 212.25
Percent Composition: C 56.59%, H 7.60%, N 13.20%, O 22.61%
Literature References: Prepn: US 1609520 (1926). Pharmacology and toxicity: G. A. Alles et al., J. Pharmacol. Exp. Ther. 89, 356 (1947).
Properties: Crystals. Slightly bitter taste. mp 124-127°. One gram dissolves in about 5 ml alcohol, 10 ml ether. Practically insol in water; insol in petr ether, aliphatic hydrocarbons. LD50 i.p. in mice: 1.506 mM/kg (Alles).
Melting point: mp 124-127°
Toxicity data: LD50 i.p. in mice: 1.506 mM/kg (Alles)
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.
Butethamate Butethamine Buthalital Sodium Buthiazide Buthiobate

Butobarbital ball-and-stick.png
Systematic (IUPAC) name
Clinical data
Trade names Soneryl
AHFS/Drugs.com International Drug Names
Legal status  ?
Routes Oral
Pharmacokinetic data
Metabolism Hepatic
Excretion Renal
CAS number 77-28-1 YesY
ATC code N05CA03
PubChem CID 6473
DrugBank DB00237
ChemSpider 6229 YesY
KEGG D02618 YesY
Chemical data
Formula C10H16N2O3 
Mol. mass 212.246 g/mol
 N (what is this?)  (verify)

Butobarbital (BAN), also called butobarbitone or butethal, Soneryl, and Neonal,[1] is a hypnotic drug which is a barbiturate derivative. It was developed by Poulenc Brothers (now part of Rhône Poulenc) in 1921.[2]