Title: Butofilolol
CAS Registry Number: 64552-17-6
CAS Name: 1-[2-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-5-fluorophenyl]-1-butanone
Additional Names: (±)-5-fluoro-2-(2-hydroxy-3-t-butylaminopropoxy)butyrophenone; (±)-2¢-[3-(tert-butylamino)-2-hydroxypropoxy]-5¢-fluorobutyrophenone
Manufacturers' Codes: CM-6805
Molecular Formula: C17H26FNO3
Molecular Weight: 311.39
Percent Composition: C 65.57%, H 8.42%, F 6.10%, N 4.50%, O 15.41%
Literature References: b-Adrenergic blocker. Prepn: H. Demarne le Florence, DE 2528147; idem, US 4302601 (1976, 1981 both to C. M. Industries). Pharmacological study: G. G. Re et al., Boll. Soc. Ital. Biol. Sper. 56, 1264 (1980), C.A. 93, 197668y (1980). GC and HPLC determn in plasma and urine: J. P. Jeanniot et al., J. Chromatogr. 278, 301 (1983). Pharmacokinetics in humans: G. Houin et al., Int. J. Clin. Pharmacol. Res. 4, 175 (1984).
Properties: Crystals from diisopropyl ether, mp 88-89°.
Melting point: mp 88-89°
Derivative Type: Maleate
CAS Registry Number: 88606-96-6
Trademarks: Cafide (Labaz)
Molecular Formula: C17H26FNO3.C4H4O4
Molecular Weight: 427.46
Percent Composition: C 59.01%, H 7.07%, F 4.44%, N 3.28%, O 26.20%
Therap-Cat: Antihypertensive.
Keywords: ?Adrenergic Blocker; Antihypertensive; Aryloxypropanolamine Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update.
Butopyronoxyl Butorphanol Butoxycaine Butralin Butriptyline

Butofilolol skeletal.svg
Systematic (IUPAC) name
Clinical data
Legal status  ?
CAS number 64552-17-6 N
ATC code None
PubChem CID 68838
ChemSpider 62071 YesY
Synonyms CM-6805
Chemical data
Formula C17H26FNO3 
Mol. mass 311.392 g/mol
 N (what is this?)  (verify)

Butofilolol (trade name Cafide) is a beta-blocker drug for the treatment of essential hypertension (high blood pressure).[1][2] It is not known to be marketed anywhere.