|Calcitonin||Calcium 2-Ethylbutanoate||Calcium 3-Aurothio-2-propanol-1-sulfonate||Calcium Acetate||Calcium Acetylsalicylate|
|Molecular weight||7036 g/mol|
|A model of the 3D structure of calciseptine, based on an NMR structure of its homologue FS2. Disulfide bridges are shown in yellow. The three residues that differ between FS2 and calciseptine are shown in red.|
Calciseptine (CaS) is a natural neurotoxin isolated from the black mamba Dendroaspis p. polylepis venom. This toxin consists of 60 amino acids with four disulfide bonds. Calciseptine specifically blocks L-type calcium channels, but not other voltage-dependent Ca2+ channels such as N-type and T-type channels.