Calcium Chloride

Title: Calcium Chloride
CAS Registry Number: 10043-52-4
Trademarks: Intergravin-orales (Werfft-Chemie)
Molecular Formula: CaCl2
Molecular Weight: 110.98
Percent Composition: Ca 36.11%, Cl 63.89%
Literature References: Forms mono-, di-, tetra- and hexahydrates. Obtained as a byproduct of the ammonia-soda (Solvay) process and as a joint product from natural salt brines: Faith, Keyes & Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 186-190. Acute toxicity: I. B. Syed, F. Hosain, Toxicol. Appl. Pharmacol. 22, 150 (1972).
Properties: Cubic crystals, granules or fused masses. Very hygroscopic. mp 772°. bp >1600°; d415 2.152. Freely sol in water (with liberation of much heat), alcohol. The commercial product is about 94-97% CaCl2, the chief impurity being Ca(OH)2. Keep well closed. LD50 i.v. in mice: 42.2 mg/kg (Syed, Hosain).
Melting point: mp 772°
Boiling point: bp >1600°
Density: d415 2.152
Toxicity data: LD50 i.v. in mice: 42.2 mg/kg (Syed, Hosain)
Derivative Type: Dihydrate
Properties: Hygroscopic granules, flakes or powder. Apparent (bulk) density: 0.835. Freely sol in water, alcohol. Commercial grades contain 73-80% CaCl2. Keep well closed.
Derivative Type: Hexahydrate
Properties: Deliquesc trigonal crystals. mp 30°. d17 1.68. Loses all H2O at 200°. Extremely sol in water, alcohol. Keep well closed.
Melting point: mp 30°
Density: d17 1.68
Use: The anhydrous form used as a drying and dehydrating agent for organic liquids and gases, and in desiccators. The dihydrate and hexahydrate forms are used for antifreeze and refrigerating solns, in fire extinguishers, etc. (a 40% soln freezes at -41°); to preserve wood, stone; manuf ice, glues, cements; fireproofing fabrics; automobile antifreeze mixtures; to melt ice and snow; as coagulant in rubber manuf, as size in admixture with starch paste; in concrete mixes to give quicker initial set and greater strength; freezeproofing of coal and ores; dust control on unpaved roads; sizing and finishing cotton fabrics; as brine for filling inflatable tires on tractors to increase traction.
Therap-Cat: Electrolyte replacement. Has been used as diuretic, urinary acidifier, antiallergic.
Therap-Cat-Vet: May be used intravenously in hypocalcemic states such as milk fever.
Keywords: Replenishers/Supplements; Electrolyte.
Calcium Chromate(VI) Calcium Citrate Calcium Cyanamide Calcium Cyanamide Citrated Calcium Cyanide

Calcium chloride
Calcium chloride
CAS number 10043-52-4 YesY
22691-02-7 (monohydrate)
10035-04-8 (dihydrate)
25094-02-4 (tetrahydrate)
7774-34-7 (hexahydrate)
PubChem 24854
ChemSpider 23237 YesY
EC number 233-140-8
DrugBank DB01164
RTECS number EV9800000
ATC code A12AA07,B05XA07, G04BA03
Jmol-3D images Image 1
Molecular formula CaCl2
Molar mass 110.98 g/mol (anhydrous)
128.999 g/mol (monohydrate)
147.014 g/mol (dihydrate)
183.045 g/mol (tetrahydrate)
219.08 g/mol (hexahydrate)
Appearance white powder
Odor odorless
Density 2.15 g/cm3 (anhydrous)
1.835 g/cm3 (dihydrate)
1.83 g/cm3 (tetrahydrate)
1.71 g/cm3 (hexahydrate)
Melting point 772 °C (anhydrous)
260 °C (monohydrate)
176 °C (dihydrate)
45.5 °C (tetrahydrate)
30 °C (hexahydrate)[1]
Boiling point 1935 °C (anhydrous)
Solubility in water 74.5 g/100mL (20 °C)
59.5 g/100 mL (0 °C)
Solubility soluble in acetone, acetic acid
Acidity (pKa) 8–9 (anhydrous)
6.5–8.0 (hexahydrate)
Refractive index (nD) 1.52
Crystal structure Orthorhombic (deformed rutile), oP6
trigonal (hexahydrate)
Space group Pnnm, No. 58
octahedral, 6-coordinate
MSDS External MSDS
GHS pictograms The exclamation-mark pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS hazard statements H319, H316, H302
GHS precautionary statements P264, P280, P270, P305+351+338, P337+313, P301+312, P330, P501
EU Index 017-013-00-2
EU classification Irritant (Xi)
R-phrases R36
S-phrases (S2), S22, S24
NFPA 704
NFPA 704.svg
LD50 1000 mg/kg (oral, rat)
Related compounds
Other anions calcium fluoride
calcium bromide
calcium iodide
Other cations Beryllium chloride
Magnesium chloride
Strontium chloride
Barium chloride
Radium chloride
Supplementary data page
Structure and
n, εr, etc.
Phase behaviour
Solid, liquid, gas
Spectral data UV, IR, NMR, MS
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Calcium chloride, CaCl2, is a salt of calcium and chlorine. It behaves as a typical ionic halide, and is solid at room temperature. Common applications include brine for refrigeration plants, ice and dust control on roads, and desiccation. Because of its hygroscopic nature, anhydrous calcium chloride must be kept in tightly sealed, air-tight containers.