Camphotamide

Title: Camphotamide
CAS Registry Number: 4876-45-3
CAS Name: 3-[(Diethylamino)carbonyl]-1-methylpyridinium salt with 4,7,7-trimethyl-3-oxobicyclo[2.2.1]heptane-2-sulfonic acid (1:1)
Additional Names: 3-(diethylcarbamoyl)-1-methylpyridinium 2-oxo-3-bornanesulfonate; camphosulfonyl-N-methylpyridine-b-diethylcarboxamide; camphetamide; camphramine
Trademarks: Tonicorine (Lematte et Boinot)
Molecular Formula: C21H32N2O5S
Molecular Weight: 424.55
Percent Composition: C 59.41%, H 7.60%, N 6.60%, O 18.84%, S 7.55%
Literature References: Prepd by the condensation of equimolar amounts of camphorsulfonic acid and N-methylnikethamide: Lab. Lematte et Boinot in P. Lebeau, M. Janot, Traité de Pharmacie Chimique vol. 4, (Paris 1955-56) p 2471; by reacting nicotinic acid with methyl camphorsulfonate and treating with diethylamine: FR 812032 (1937 to Soc. Franc. Recherches Biochim.), C.A. 32, 1052 (1938).
Properties: Minute crystals, mp 174-175°. Slight camphor-like odor. Bitter taste with sweet aftertaste. Soluble in water, alcohol, ether. Insol in benzene, other hydrocarbons.
Melting point: mp 174-175°
Therap-Cat: CNS stimulant.
Keywords: CNS Stimulant.
Status: This monograph has been retired and is no longer subject to revision or update.
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