Carazolol

Title: Carazolol
CAS Registry Number: 57775-29-8
CAS Name: 1-(9H-Carbazol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol
Manufacturers' Codes: BM-51052
Trademarks: Conducton (Klinge); Suacron (Praemix)
Molecular Formula: C18H22N2O2
Molecular Weight: 298.38
Percent Composition: C 72.46%, H 7.43%, N 9.39%, O 10.72%
Literature References: b-Adrenergic blocker. Prepn: H. Leinert et al., DE 2240599 (1974 to Boehringer, Mann.), C.A. 80, 133455a (1974). Comparative study of cardiac action: W. Bartsch et al., Arzneim.-Forsch. 27, 1022 (1977). Initial clinico-pharmacological study: E. Chorianopoulos et al., Herz/Kreislauf 9, 965 (1977), C.A. 88, 164460t (1978). Receptor binding studies: G. Kaiser et al., Arch. Pharmacol. 305, 41 (1978); R. B. Innis et al., Life Sci. 24, 2255 (1979). Use in treatment of stress syndrome in pigs: G. Ballarini, F. Guizzardi, Tieraerztl. Umsch. 36, 171 (1981).
Derivative Type: Hydrochloride
Molecular Formula: C18H23ClN2O2
Molecular Weight: 334.84
Percent Composition: C 64.57%, H 6.92%, Cl 10.59%, N 8.37%, O 9.56%
Properties: Crystals, mp 234-235°.
Melting point: mp 234-235°
Therap-Cat: Antihypertensive, antianginal, antiarrhythmic.
Therap-Cat-Vet: Treatment of stress in pigs.
Keywords: ?Adrenergic Blocker; Antianginal; Antiarrhythmic; Antihypertensive; Aryloxypropanolamine Derivatives.
Carbachol Carbacrylic Resins Carbadox Carbamazepine Carbamide Peroxide

Carazolol
Carazolol.svg
Systematic (IUPAC) name
1-(9H-carbazol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
Clinical data
AHFS/Drugs.com International Drug Names
Legal status  ?
Identifiers
CAS number 57775-29-8
ATCvet code QC07AA90
PubChem CID 71739
IUPHAR ligand 569
ChemSpider 64783
UNII 29PW75S82A YesY
Chemical data
Formula C18H22N2O2 
Mol. mass 298.38

Carazolol is a high affinity antagonist/partial inverse agonist (also referred to as a beta blocker) of the β-adrenergic receptor.[1]