Carbadox

Title: Carbadox
CAS Registry Number: 6804-07-5
CAS Name: (2-Quinoxalinylmethylene)hydrazinecarboxylic acid methyl ester N,N¢-dioxide
Additional Names: 3-(2-quinoxalinylmethylene)carbazic acid methyl ester N,N¢-dioxide; methyl 3-(2-quinoxalinylmethylene)carbazate N1,N4-dioxide; 2-formylquinoxaline-1,4-dioxide carbomethoxyhydrazone
Manufacturers' Codes: GS-6244
Trademarks: Fortigro (Pfizer); Mecadox (Pfizer)
Molecular Formula: C11H10N4O4
Molecular Weight: 262.22
Percent Composition: C 50.38%, H 3.84%, N 21.37%, O 24.41%
Literature References: Prepn: Johnston, BE 669353; idem, US 3371090; US 3433871 (1964, 1968, 1969, all to Pfizer). Animal studies: Thrasher et al., J. Anim. Sci. 26, 911 (1967); Kornegay et al., ibid. 27, 1134 (1968).
Properties: Minute yellow crystals, mp 239.5-240°. uv max (water): 236, 251, 303, 366, 373 nm (e 11000, 10900, 36400, 16100, 16200). Practically insol in water.
Melting point: mp 239.5-240°
Absorption maximum: uv max (water): 236, 251, 303, 366, 373 nm (e 11000, 10900, 36400, 16100, 16200)
Therap-Cat-Vet: Antimicrobial.
Carbamazepine Carbamide Peroxide Carbamyl Chloride Carbanilic Acid Carbanilide

Carbadox
Carbadox.svg
Identifiers
CAS number 6804-07-5 N
PubChem 5353472
ChemSpider 10606106 YesY
EC number 229-879-0
ChEMBL CHEMBL13779 YesY
RTECS number FE2779000
Jmol-3D images Image 1
Properties
Molecular formula C11H10N4O4
Molar mass 262.22 g/mol
Appearance Yellow crystals
Density 1.44 g/cm3
Melting point 239.5 °C
Solubility in water Insoluble
Hazards
EU classification F, T
R/S statement R: R45, R11, R22
S: S53, S45
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Carbadox is a drug that combats bacterial infection in swine, particularly swine dysentery. In early 2004 it was banned by the Canadian government as a livestock feed additive and for human consumption, since it is carcinogenic and induces birth defects, as was shown in animal experiments.[1] The European Union also forbids the use of Carbadox at any level.[citation needed] It is approved in the United States for use in swine for up to 42 days before slaughter.[citation needed] Australia also forbids the use of Carbadox for Food Producing Animals.[2]