Title: Carbazochrome Salicylate
CAS Registry Number: 13051-01-9
CAS Name: 2-Hydroxybenzoic acid monosodium salt compd with 2-(1,2,3,6-tetrahydro-3-hydroxy-1-methyl-6-oxo-5H-indol-5-ylidene)hydrazinecarboxamide (1:1)
Additional Names: 3-hydroxy-1-methyl-1,5,6-indolinedione semicarbazone compd with sodium salicylate; adrenochrome semicarbazone compd with sodium salicylate; adrenochrome monosemicarbazone sodium salicylate complex
Trademarks: Adenogen; Adrestat-F (Organon)
Molecular Formula: C17H17N4NaO6
Molecular Weight: 396.33
Percent Composition: C 51.52%, H 4.32%, N 14.14%, Na 5.80%, O 24.22%
Line Formula: C10H12N4O3.C7H5NaO3
Literature References: Prepd by refluxing adrenochrome semicarbazone and Na salicylate in 30% methanol: Iwao et al., JP 57 546 (1957 to Tanabe), C.A. 52, 4693 (1958).
Properties: Orange-red powder, mp 196-197.5° (dec). Soly in water (25°): 0.61 mg/ml. Practically insol in ether, chloroform. pH of 10% aq soln 6.7 to 7.3. See also Adrenochrome.
Melting point: mp 196-197.5° (dec)
Therap-Cat-Vet: Systemic hemostatic for capillary bleeding from increased capillary permeability.