Carbazochrome Sodium Sulfonate

Title: Carbazochrome Sodium Sulfonate
CAS Registry Number: 51460-26-5
CAS Name: 5-[(Aminocarbonyl)hydrazono]-2,3,5,6-tetrahydro-1-methyl-6-oxo-1H-indole-2-sulfonic acid monosodium salt
Additional Names: 5,6-dihydro-1-methyl-5,6-dioxo-2-indolinesulfonic acid 5-semicarbazone sodium salt; epinochrome-2-sulfonic acid 5-monosemicarbazone sodium salt; 1-methyl-5-semicarbazono-6-oxo-2,3,5,6-tetrahydroindole-2-sulfonic acid sodium salt; sodium 5,6-dihydro-1-methyl-5,6-dioxo-2-indolinesulfonate 5-semicarbazone
Manufacturers' Codes: AC-17
Trademarks: Adenaron (Kowa); Adona (Tanabe Seiyaku); Carbazon (Hokuriku); Donaseven (Yakult); Emex (Archifar); Odanon (Towa Yakuhin); Tazin (Grelan)
Molecular Formula: C10H11N4NaO5S
Molecular Weight: 322.27
Percent Composition: C 37.27%, H 3.44%, N 17.39%, Na 7.13%, O 24.82%, S 9.95%
Literature References: Prepn: Iwao, Pharm. Bull. 4, 251 (1956), C.A. 51, 6860f (1957); GB 795184 (1958 to Gohei Tanabe). Revision of structure from a 3- to a 2-sulfonic acid: Kawazu et al., J. Heterocycl. Chem. 10, 1059 (1973).
Properties: Yellow-orange needles from aq methanol, dec 227-228° (free acid dec 195°). Soluble in water.
Therap-Cat: Hemostatic.
Keywords: Hemostatic.
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