Title: Carbobenzoxy Chloride
CAS Registry Number: 501-53-1
CAS Name: Carbonochloridic acid phenylmethyl ester
Additional Names: benzyl chloroformate; chloroformic acid benzyl ester; benzylcarbonyl chloride
Molecular Formula: C8H7ClO2
Molecular Weight: 170.59
Percent Composition: C 56.33%, H 4.14%, Cl 20.78%, O 18.76%
Literature References: Prepn by action of phosgene absorbed in toluene on benzyl alcohol: Carter et al., Org. Synth. 23, 13 (1943); by reacting carbonyl chloride and benzyl alcohol at -20 to -30°: Farthing, J. Chem. Soc. 1950, 3213.
Properties: Oily liquid; acrid odor; lacrimator. bp20 103°; bp7 85-87°. Dec to CO2 and benzyl chloride upon heating at 100-155°.
Boiling point: bp20 103°; bp7 85-87°
Use: In peptide synthesis to block the amino group.