Cassamine

Title: Cassamine
CAS Registry Number: 471-71-6
CAS Name: [1S-(1a,4aa,4bb,7E,8b,8aa,10ab)]-7-[2-[2-(Dimethylamino)ethoxy]-2-oxoethylidene]tetradecahydro-1,4a,8-trimethyl-9-oxo-1-phenanthrenecarboxylic acid methyl ester
Additional Names: (E)-13-(carboxymethylene)-14a-methyl-7-oxopodocarpan-16-oic acid 13-[2-(dimethylamino)ethyl]methyl ester
Molecular Formula: C25H39NO5
Molecular Weight: 433.58
Percent Composition: C 69.25%, H 9.07%, N 3.23%, O 18.45%
Literature References: Extracted from the bark of Erythrophleum guineense G. Don., Leguminosae. Isoln: Engel, Tondeur, Helv. Chim. Acta 32, 2364 (1949). Structure: Arya, Engel, ibid. 44, 1650 (1961).
Properties: Crystals from pentane, mp 86-87°. [a]D20 -56° (ethanol). uv max: 225 nm (log e 4.2). Soluble in petr ether.
Melting point: mp 86-87°
Optical Rotation: [a]D20 -56° (ethanol)
Absorption maximum: uv max: 225 nm (log e 4.2)
Derivative Type: Hydrochloride
Molecular Formula: C25H39NO5.HCl
Molecular Weight: 470.04
Percent Composition: C 63.88%, H 8.58%, N 2.98%, O 17.02%, Cl 7.54%
Properties: Crystals from acetone, dec 214-217°. [a]D17 -48° (c = 0.65 in water).
Optical Rotation: [a]D17 -48° (c = 0.65 in water)
Derivative Type: Sulfate
Molecular Formula: C25H39NO5.H2SO4
Molecular Weight: 531.66
Percent Composition: C 56.48%, H 7.77%, N 2.63%, O 27.08%, S 6.03%
Properties: Crystals from alcohol + ether, mp 191-194°. [a]D17 -49.5° (c = 0.47 in water).
Melting point: mp 191-194°
Optical Rotation: [a]D17 -49.5° (c = 0.47 in water)
Status: This monograph has been retired and is no longer subject to revision or update.
Castanea Castanospermine Castor Oil, Hydrogenated Catalase Catalposide