Title: Cefminox
CAS Registry Number: 84305-41-9
CAS Name: (6R,7S)-7-[[[[(2S)-2-Amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Additional Names: 7b-(2-D-amino-2-carboxyethylthioacetamido)-7a-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-3-cephem-4-carboxylic acid
Molecular Formula: C16H21N7O7S3
Molecular Weight: 519.58
Percent Composition: C 36.99%, H 4.07%, N 18.87%, O 21.56%, S 18.51%
Literature References: Semisynthetic broad spectrum cephamycin antibiotic. Prepn: BE 880656, K. Iwamatsu et al., US 4357331 (1980, 1982 both to Meiji Seika). Synthesis, biological activity: eidem, J. Antibiot. 36, 229 (1983). Structure-activity studies: S. Inouye et al., ibid. 37, 1403 (1984). Proposed mechanism of action: T. Tsuruoka et al., Eur. J. Biochem. 151, 209 (1985). In vitro, in vivo antibacterial activity compared with that of other cephalosporins: S. Inouye et al., Antimicrob. Agents Chemother. 26, 722 (1984). Activity against gram-negative infections in mice: T. Watanabe et al., Drugs Exp. Clin. Res. 10, 293 (1984). Toxicity studies: M. Kurebe et al., Jpn. J. Antibiot. 37, 847 (1984). Series of articles on pharmacokinetics, early clinical trials, treatment of urinary tract and respiratory infections: Chemotherapy (Tokyo) 32, Suppl. 5 (1984) 561 pp.
Derivative Type: Sodium salt heptahydrate
Manufacturers' Codes: MT-141
Trademarks: Meicelin (Meiji Seika)
Molecular Formula: C16H20N7NaO7S3.7H2O
Molecular Weight: 667.66
Percent Composition: C 28.78%, H 5.13%, N 14.69%, Na 3.44%, O 33.55%, S 14.41%
Properties: Crystals from ethanol-water, mp 90-91°. LD50 in male, female mice (mg/kg): 6100, 5200 i.v.; in male, female rats (mg/kg): 6600, 5700 i.v.; 8600, 8550 i.p.; >15000, >15000 s.c. or orally (Kurebe).
Melting point: mp 90-91°
Toxicity data: LD50 in male, female mice (mg/kg): 6100, 5200 i.v.; in male, female rats (mg/kg): 6600, 5700 i.v.; 8600, 8550 i.p.; >15000, >15000 s.c. or orally (Kurebe)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Cephamycins.
Cefodizime Cefonicid Cefoperazone Ceforanide Cefoselis

Systematic (IUPAC) name
(6R,7S)-7-(((((2S)-2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
Clinical data
AHFS/Drugs.com International Drug Names
Legal status Prescription only
Routes IM, IV
CAS number 84305-41-9 YesY
ATC code J01DC12
PubChem CID 71141
ChemSpider 64286 N
UNII PW08Y13465 YesY
KEGG D07642 YesY
Chemical data
Formula C16H21N7O7S3 
Mol. mass 519.57 g/mol
 N (what is this?)  (verify)

Cefminox (INN) is a second-generation cephalosporin antibiotic.[1][2]