Title: Cefoselis
CAS Registry Number: 122841-10-5
CAS Name: (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Additional Names: (syn)-7b-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-[3-amino-2-(2-hydroxyethyl)-1-pyrazolio]methyl-3-cephem-4-carboxylate; (-)-5-amino-2-[[(6R,7R)-7-[2-(2-amino-4-thiazolyl)glyoxylamido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-(2-hydroxyethyl)pyrazolium hydroxide inner salt 72-(Z)-(O-methyloxime)
Molecular Formula: C19H22N8O6S2
Molecular Weight: 522.56
Percent Composition: C 43.67%, H 4.24%, N 21.44%, O 18.37%, S 12.27%
Literature References: Fourth generation cephalosporin antibiotic. Prepn: K. Sakane et al., EP 307804; eidem, US 4952578 (1989, 1990 both to Fujisawa); H. Ohki et al., J. Antibiot. 46, 359 (1993). In vitro activity and b-lactamase stability: H. C. Neu et al., Antimicrob. Agents Chemother. 37, 566 (1993). Clinical pharmacokinetics: R. Wise et al., ibid. 38, 2369 (1994). Series of articles on activity, clinical pharmacology and therapeutic efficacy: Chemotherapy (Tokyo) 42, Suppl. 3, 1-464 (1994).
Derivative Type: Sulfate
CAS Registry Number: 122841-12-7
Manufacturers' Codes: FK-037
Trademarks: Wincef (Fujisawa)
Molecular Formula: C19H22N8O6S2.H2SO4
Molecular Weight: 620.64
Percent Composition: C 36.77%, H 3.90%, N 18.05%, O 25.78%, S 15.50%
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Cephalosporins.
Cefotetan Cefotiam Cefoxitin Cefozopran Cefpimizole

CAS number 122841-10-5 YesY
PubChem 9589475
ChemSpider 16736411 YesY
Jmol-3D images Image 1
Molecular formula C19H22N8O6S2
Molar mass 522.56 g mol−1
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Cefoselis is a cephalosporin.