Cetamolol

Title: Cetamolol
CAS Registry Number: 34919-98-7
CAS Name: 2-[2-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]phenoxy]-N-methylacetamide
Additional Names: 2-[o-[3-(t-butylamino)-2-hydroxypropoxy]phenoxy]-N-methylacetamide; (±)-1-t-butylamino-3-(o-N-methylcarbamoylmethoxyphenoxy)propan-2-ol
Molecular Formula: C16H26N2O4
Molecular Weight: 310.39
Percent Composition: C 61.91%, H 8.44%, N 9.03%, O 20.62%
Literature References: Cardioselective b1-adrenergic blocker. Prepn: BE 767781; D. J. Lecount, C. J. Squire, US 4059622 (1971, 1977 both to ICI). Cardiovascular effects in dogs: G. Beaulieu et al., Can. J. Physiol. Pharmacol. 63, 610 (1984). Determn in human serum: M. D. Stern, Clin. Biochem. 17, 162 (1984). Pharmacology and pharmacodynamics in humans: M. A. Klausner et al., Curr. Ther. Res. 36, 379 (1984); J. Coelho et al., Br. J. Clin. Pharmacol. 19, 411 (1985). Evaluation in hypertensive patients: W. B. White et al., Clin. Pharmacol. Ther. 39, 664 (1986).
Properties: Crystals from benzene-petr ether, mp 96-97°.
Melting point: mp 96-97°
Derivative Type: Hydrochloride
CAS Registry Number: 77590-95-5
Manufacturers' Codes: AI-27303; ICI-72222
Trademarks: Betacor (Ayerst)
Molecular Formula: C16H26N2O4.HCl
Molecular Weight: 346.85
Percent Composition: C 55.40%, H 7.85%, N 8.08%, O 18.45%, Cl 10.22%
Therap-Cat: Antihypertensive.
Keywords: ?Adrenergic Blocker; Antihypertensive; Aryloxypropanolamine Derivatives.
Cethexonium Bromide Cethromycin Cetiedil Cetotiamine Cetoxime

Cetamolol
Cetamolol.svg
Identifiers
CAS number 77590-95-5 (hydrochloride)
PubChem 53698
ChemSpider 48483
Jmol-3D images Image 1
Properties
Molecular formula C16H26N2O4
Molar mass 310.39 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Cetamolol is a beta adrenergic antagonist.[1]