Cetiedil

Title: Cetiedil
CAS Registry Number: 14176-10-4
CAS Name: a-Cyclohexyl-3-thiopheneacetic acid 2-(hexahydro-1H-azepin-1-yl)ethyl ester
Additional Names: a-cyclohexyl-a-(3-thienyl)acetic acid 2-hexamethyleneiminoethyl ester
Molecular Formula: C20H31NO2S
Molecular Weight: 349.53
Percent Composition: C 68.72%, H 8.94%, N 4.01%, O 9.15%, S 9.17%
Literature References: Prepn: Pons, Robba, FR 1460571 and Pons et al., FR M5504 (1966, 1967, both to Innothera), C.A. 68, 59429d (1968); 71, 91286c (1969). Prepn and activity: Robba, LeGuen, Chim. Ther. 2, 120 (1967). Antisickling effect: T. Asakura et al., Proc. Natl. Acad. Sci. USA 77, 2955 (1980); L. R. Berkowitz, E. P. Orringer, J. Clin. Invest. 68, 1215 (1981).
Derivative Type: Citrate
CAS Registry Number: 16286-69-4
Trademarks: Stratene (Innothera; Sigma-Tau); Vasocet (Winthrop)
Molecular Formula: C20H31NO2S.C6H8O7
Molecular Weight: 541.65
Percent Composition: C 57.65%, H 7.26%, N 2.59%, O 26.58%, S 5.92%
Properties: Crystals from ethanol-ether, mp 115°.
Melting point: mp 115°
Derivative Type: Hydrochloride
Molecular Formula: C20H31NO2S.HCl
Molecular Weight: 385.99
Percent Composition: C 62.23%, H 8.36%, N 3.63%, O 8.29%, S 8.31%, Cl 9.18%
Properties: Crystals from acetonitrile, mp 152° (Robba, LeGuen); also mp 143° (Pons, Robba).
Melting point: mp 152° (Robba, LeGuen); mp 143° (Pons, Robba)
Therap-Cat: Vasodilator (peripheral).
Keywords: Vasodilator (Peripheral).
Cetotiamine Cetoxime Cetraric Acid Cetraxate Cetrimonium Bromide

Cetiedil
Cetiedil small.png
Systematic (IUPAC) name
2-(azepan-1-yl)ethyl 2-cyclohexyl-2-(thiophen-3-yl)acetate
Clinical data
Legal status  ?
Identifiers
CAS number 14176-10-4 YesY
ATC code C04AX26
PubChem CID 66384
ChemSpider 59759 N
UNII 621RT200TO YesY
Chemical data
Formula C20H31NO2S 
Mol. mass 349.53064
 N (what is this?)  (verify)

Cetiedil is a vasodilator and an anti-sickling agent.