Chloroxine

Title: Chloroxine
CAS Registry Number: 773-76-2
CAS Name: 5,7-Dichloro-8-quinolinol
Additional Names: 5,7-dichloro-8-hydroxyquinoline
Trademarks: Capitrol (Westwood)
Molecular Formula: C9H5Cl2NO
Molecular Weight: 214.05
Percent Composition: C 50.50%, H 2.35%, Cl 33.13%, N 6.54%, O 7.47%
Literature References: Prepd by chlorinating 8-quinolinol: Hebebrand, Ber. 21, 2977 (1888), F. J. Welcher, Organic Analytical Reagents vol. I (Van Nostrand, 1947) pp 328-329.
Properties: Crystals from alc, mp 179-180°. Soluble in benzene, acetone; slightly sol in cold alcohol, acetic acid; readily sol in sodium and potassium hydroxides and in acids, forming yellow solns.
Melting point: mp 179-180°
Use: Analytical reagent.
Therap-Cat: Antiseborrheic.
Keywords: Antiseborrheic; Antiseptic/Disinfectant; Quinolines.
Chloroxylenol Chlorozotocin Chlorphenesin Chlorphenesin Carbamate Chlorpheniramine

Chloroxine
Chloroxine.png
Clinical data
Trade names Capitrol
AHFS/Drugs.com Micromedex Detailed Consumer Information
Legal status -only (US)
Identifiers
ATC code None
PubChem CID 2722
ChemSpider 2621
UNII 2I8BD50I8B
ChEMBL CHEMBL1200596
Synonyms cloroxinum, kloroxin, chlorquinol, dichlorchinolinolum, halquinol(s)
Chemical data
Formula C9H5Cl2NO 
Mol. mass 214 g/mol

Chloroxine (trade name Capitrol; Kloroxin, Dichlorchinolinol, chlorquinol, halquinol(s));[citation needed] Latin cloroxinum, dichlorchinolinolum) is an antibacterial drug.[1] Oral formulations (under trade name such as Endiaron[2]) are used in infectious diarrhea, disorders of the intestinal microflora (e.g. after antibiotic treatment), giardiasis, inflammatory bowel disease. It is also useful for dandruff and seborrheic dermatitis.,[3] as used in shampoos (Capitrol) and dermal creams like (Valpeda, Triaderm).