Title: Chlorphenesin
CAS Registry Number: 104-29-0
CAS Name: 3-(4-Chlorophenoxy)-1,2-propanediol
Additional Names: p-chlorophenyl a-glyceryl ether
Trademarks: Adermykon; Mycil (BDH)
Molecular Formula: C9H11ClO3
Molecular Weight: 202.63
Percent Composition: C 53.35%, H 5.47%, Cl 17.50%, O 23.69%
Literature References: Prepd by condensing equimol amts of p-chlorophenol and glycidol in the presence of a tertiary amine or a quaternary ammonium salt as catalyst: Bradley, Forrest, GB 628497 (1949 to British Drug Houses).
Properties: Crystals, mp 77-79°. Soly in water is less than 1%, may be increased by the addition of solubilizers such as ethylurea or propylene glycol: Berger et al., US 2468423 (1949 to British Drug Houses).
Melting point: mp 77-79°
Therap-Cat: Antifungal (topical).
Keywords: Antifungal (Synthetic).
Chlorphenesin Carbamate Chlorpheniramine Chlorphenoxamide Chlorphenoxamine Chlorphentermine

Systematic (IUPAC) name
Clinical data
AHFS/ Micromedex Detailed Consumer Information
Legal status  ?
Pharmacokinetic data
Excretion urine
CAS number 886-74-8
ATC code D01AE07
PubChem CID 2724
ChemSpider 2623
KEGG D00770
Chemical data
Formula C10H12ClNO4 
Mol. mass 245.660 g/mol
Physical data
Melt. point 86–92 °C (187–198 °F)

Chlorphenesin (Maolate, Musil) is a centrally acting muscle relaxant used to treat muscle pain and spasms.[1][2] Chlorphenesin is no longer used for this purpose in most developed nations due to the availability of much safer spasmolytics such as benzodiazepines.

Other central effects include sedation, anxiolytion, and dizziness. It also has antifungal and some antibacterial properties and is thus classified as an antifungal for topical use by the WHO.[3]