Title: Chlorproguanil
CAS Registry Number: 537-21-3
CAS Name: N-(3,4-Dichlorophenyl)-N¢-(1-methylethyl)imidodicarbonimidic diamide
Additional Names: 1-(3,4-dichlorophenyl)-5-isopropylbiguanide; N1-3,4-dichlorophenyl-N5-isopropylbiguanide; N1-3,4-dichlorophenyl-N5-isopropyldiguanide
Manufacturers' Codes: M-5943
Molecular Formula: C11H15Cl2N5
Molecular Weight: 288.18
Percent Composition: C 45.85%, H 5.25%, Cl 24.60%, N 24.30%
Literature References: Method of prepn: Crowther et al., J. Chem. Soc. 1951, 1780; Curd et al., US 2544827 (1951); Crowther et al., GB 667116 (1952) (both to ICI). Clinical trial with dapsone, q.v., in drug-resistant malaria: T. Mutabingwa et al., Lancet 358, 1218 (2001).
Derivative Type: Hydrochloride
CAS Registry Number: 15537-76-5
Trademarks: Lapudrine (Zeneca)
Molecular Formula: C11H15Cl2N5.HCl
Molecular Weight: 324.64
Percent Composition: C 40.70%, H 4.97%, Cl 32.76%, N 21.57%
Properties: Crystals, mp 246-247°. Soly in water: 1 g/100 ml. Solns may be boiled without dec.
Melting point: mp 246-247°
Therap-Cat: Antimalarial.
Keywords: Antimalarial.
Chlorpropamide Chlorpropham Chlorprothixene Chlorpyrifos Chlorquinaldol

CAS number 537-21-3
PubChem 22323
ChemSpider 20950
UNII 8O3249M729 YesY
Jmol-3D images Image 1
Molecular formula C11H15Cl2N5
Molar mass 288.18 g/mol
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Chlorproguanil is an antimalarial drug.