Choline Chloride

Title: Choline Chloride
CAS Registry Number: 67-48-1
CAS Name: 2-Hydroxy-N,N,N-trimethylethanaminium chloride
Trademarks: Biocolina; Hepacholine; Lipotril
Molecular Formula: C5H14ClNO
Molecular Weight: 139.62
Percent Composition: C 43.01%, H 10.11%, Cl 25.39%, N 10.03%, O 11.46%
Line Formula: [HOCH2CH2N+(CH3)3]Cl-
Literature References: Prepn: Klein, Kapp, US 2623901 (1952 to Nopco Chem.). Polymorphism: Collin, J. Am. Chem. Soc. 79, 6086 (1957). Enhancement of human serial learning: N. Sitaram et al., Life Sci. 22, 1555 (1978); eidem, Science 201, 274 (1978). Toxicity data: Hartung, Cornish, Toxicol. Appl. Pharmacol. 12, 486 (1968).
Properties: Deliquesc crystals. Very sol in water or alcohol. The aq soln is practically neutral. Keep tightly closed. LD50 in rats (g/kg): 0.400 i.p.; 6.64 orally (Hartung, Cornish).
Toxicity data: LD50 in rats (g/kg): 0.400 i.p.; 6.64 orally (Hartung, Cornish)
Therap-Cat: Lipotropic.
Therap-Cat-Vet: Nutritional factor. Dietary source of choline (lipotropic factor) in poultry.
Keywords: Lipotropic.
Choline Dehydrocholate Choline Dihydrogen Citrate Choline Esterase Choline Salicylate Choline Theophyllinate