Ciclosidomine

Title: Ciclosidomine
CAS Registry Number: 66564-16-7
CAS Name: N-(Cyclohexylcarbonyl)-3-(4-morpholinyl)sydnone imine
Molecular Formula: C13H20N4O3
Molecular Weight: 280.32
Percent Composition: C 55.70%, H 7.19%, N 19.99%, O 17.12%
Literature References: Peripheral vasodilator similar to molsidomine. Prepn: FR 1551013; GB 1198283 (1968, 1970 both to Boehringer, Ing.). Clinical evaluation: J. Vos, E. J. D. Mees, Br. J. Clin. Pharmacol. 8, 155 (1979). Effect on blood pressure and heart rate: R. G. Shanks et al., ibid. 18, 232 (1984). Tissue distribution and excretion: M. R. Matteo et al., Arzneim.-Forsch. 35, 329 (1985).
Derivative Type: Hydrochloride
CAS Registry Number: 26209-07-4
Manufacturers' Codes: PR-G 138-Cl
Trademarks: Neopres (Boehringer, Ing.)
Molecular Formula: C13H20N4O3.HCl
Molecular Weight: 316.78
Percent Composition: C 49.29%, H 6.68%, N 17.69%, O 15.15%, Cl 11.19%
Properties: Crystalline powder, mp 187°.
Melting point: mp 187°
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive.
Status: This monograph has been retired and is no longer subject to revision or update.
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