Clidinium Bromide

Title: Clidinium Bromide
CAS Registry Number: 3485-62-9
CAS Name: 3-[(Hydroxydiphenylacetyl)oxy]-1-methyl-1-azoniabicyclo[2.2.2]octane bromide
Additional Names: 3-hydroxy-1-methylquinuclidinium bromide benzilate; 1-methyl-3-benziloyloxyquinuclidinium bromide; 3-benziloyloxy-1-azabicyclo[2.2.2]octane methobromide
Manufacturers' Codes: Ro-2-3773
Trademarks: Quarzan (Roche)
Molecular Formula: C22H26BrNO3
Molecular Weight: 432.35
Percent Composition: C 61.12%, H 6.06%, Br 18.48%, N 3.24%, O 11.10%
Literature References: Anticholinergic. Prepn: Sternbach, US 2648667 (1953 to Hoffmann-La Roche). Comprehensive description: B. C. Rudy, B. Z. Senkowski, Anal. Profiles Drug Subs. 2, 145-161 (1973).
Properties: Crystals from methanol + acetone + ether, mp 240-241°.
Melting point: mp 240-241°
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic; Antimuscarinic.
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