Title: Clobenzorex
CAS Registry Number: 13364-32-4
CAS Name: (+)-N-[(2-Chlorophenyl)methyl]-a-methylbenzeneethanamine
Additional Names: (+)-N-(o-chlorobenzyl)-a-methylphenethylamine; d-N-(1-phenyl-2-propyl)-2-chlorobenzylamine
Molecular Formula: C16H18ClN
Molecular Weight: 259.77
Percent Composition: C 73.98%, H 6.98%, Cl 13.65%, N 5.39%
Literature References: Prepn and pharmacology: J. R. Boissier, R. Ratouis, FR 1429306 (1966 to Soc. Ind. Fabric. Antibiot.), C.A. 66, 46195h (1967); J. R. Boissier et al., Ann. Pharm. Fr. 24, 57 (1966). Synthesis of labelled compound: J. Lintermans et al., J. Labelled Compd. 6, 289 (1970). Metabolic studies: M. Thomasset et al., Experientia 26, 692 (1970); B. Glasson et al., Arzneim.-Forsch. 21, 1985 (1971).
Properties: bp0.1 132-134°.
Boiling point: bp0.1 132-134°
Derivative Type: Hydrochloride
CAS Registry Number: 5843-53-8
Manufacturers' Codes: Ba-7205; SD-271-12
Trademarks: Dinintel (Diamant); Rexigen (Bago)
Molecular Formula: C16H18ClN.HCl
Molecular Weight: 296.23
Percent Composition: C 64.87%, H 6.46%, Cl 23.94%, N 4.73%
Properties: Crystals, mp 182-183° (isopropanol). [a]D20 +26.3° (water). Sol in water, ethanol. Slightly sol in methanol, chloroform. LD50 i.p. in mice: 103 mg/kg (Boissier et al.).
Melting point: mp 182-183° (isopropanol)
Optical Rotation: [a]D20 +26.3° (water)
Toxicity data: LD50 i.p. in mice: 103 mg/kg (Boissier et al.)
Therap-Cat: Anorexic.
Keywords: Anorexic.
Clobenztropine Clobetasone Clobuzarit Clocinizine Cloconazole

Clobenzorex structure.svg
Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
Legal status  ?
Routes Oral
CAS number 13364-32-4
ATC code A08AA08
PubChem CID 71675
ChemSpider 64732 YesY
UNII 4A5352XI2A YesY
KEGG D07115 YesY
Synonyms (+)-N-(2-chlorobenzyl)amphetamine
Chemical data
Formula C16H18ClN 
Mol. mass 259.78 g/mol
 YesY (what is this?)  (verify)

Clobenzorex (Asenlix, Dinintel, Finedal, Rexigen) is a stimulant drug of the phenethylamine and amphetamine chemical classes used as an appetite suppressant. The drug is legally distributed in Mexico under the trade name Asenlix by Aventis.

Chemically, clobenzorex is an N-substituted amphetamine analog that is converted to d-amphetamine soon after ingestion. In commercial production, clobenzorex is supplied in 30 mg doses as the hydrochloride salt in green-tinted capsules. The drug gained use as a prescription anorectic in the 1970s; however, adverse reactions were eventually observed, which led to the prohibition of clobenzorex in the United States and certain other countries.[1]

In the United States, clobenzorex tablets (among other varieties of stimulants, such as amphetamine) have been used by athletes who ingest the drug to reduce fatigue, increase attention, and improve reaction times during athletic activities. The green-tinted Asenlix capsules (generic forms can be seen as half light green, half dark green capsules marked "IFA") are known as "greenies" among US baseball players, a slang term that in current use has expanded to generically refer to any amphetamine class stimulant.