Clocinizine

Title: Clocinizine
CAS Registry Number: 298-55-5
CAS Name: 1-[(4-Chlorophenyl)phenylmethyl]-4-(3-phenyl-2-propenyl)piperazine
Additional Names: 1-(p-chloro-a-phenylbenzyl)-4-cinnamylpiperazine; 1-cinnamyl-4-(4-chlorobenzhydryl)piperazine; cliocinizine
Molecular Formula: C26H27ClN2
Molecular Weight: 402.96
Percent Composition: C 77.50%, H 6.75%, Cl 8.80%, N 6.95%
Literature References: Prepn: GB 809760 (1959 to Janssen). HPLC determn in cough-cold preparations: G. Cavazzutti et al., J. Liq. Chromatogr. 18, 227 (1995).
Derivative Type: Hydrochloride
Properties: Crystals, mp 200-201°.
Melting point: mp 200-201°
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Piperazines.
Cloconazole Clocortolone Clodinafop-Propargyl Clodronic Acid Clofarabine

Clocinizine
Clocinizine.png
Systematic (IUPAC) name
1-[(4-chlorophenyl)-phenylmethyl]-4-[(E)-3-phenylprop-2-enyl]piperazine
Clinical data
AHFS/Drugs.com International Drug Names
Legal status  ?
Routes Oral
Identifiers
CAS number 298-55-5
ATC code None
PubChem CID 5375618
ChemSpider 4525064
UNII 8HQJ711KH8 YesY
Chemical data
Formula C26H27ClN2 
Mol. mass 402.96 g/mol

Clocinizine is a first-generation antihistamine of the phenylpiperazine class.