Clomestrone

Title: Clomestrone
CAS Registry Number: 4091-75-2
CAS Name: (16a)-16-Chloro-3-methoxyestra-1,3,5(10)-trien-17-one
Additional Names: 16a-chloroestrone 3-methyl ether
Trademarks: Arterolo (Nuovo Cons.); Atheran
Molecular Formula: C19H23ClO2
Molecular Weight: 318.84
Percent Composition: C 71.57%, H 7.27%, Cl 11.12%, O 10.04%
Literature References: Prepn: Mueller et al., J. Am. Chem. Soc. 80, 1769 (1958); Mueller, US 2855411 (1958 to Searle); Ravizza, CH 343396 (1959). Alternate route: Labs. Sobio, FR 1350100 (1964).
Properties: Crystals from chloroform, mp 179-180°. [a]D +161° (chloroform).
Melting point: mp 179-180°
Optical Rotation: [a]D +161° (chloroform)
Clometacin Clometocillin Clomiphene Clomipramine Clomocycline