Title: Clonixin
CAS Registry Number: 17737-65-4
CAS Name: 2-[(3-Chloro-2-methylphenyl)amino]-3-pyridinecarboxylic acid
Additional Names: 2-(3-chloro-o-toluidino)nicotinic acid; 2-(2-methyl-3-chloroanilino)nicotinic acid; 2-(3-chloro-2-methylanilino)nicotinic acid; clonixic acid
Manufacturers' Codes: CBA-93626; Sch-10304
Molecular Formula: C13H11ClN2O2
Molecular Weight: 262.69
Percent Composition: C 59.44%, H 4.22%, Cl 13.50%, N 10.66%, O 12.18%
Literature References: Nonsteroidal anti-inflammatory agent. Prepn: M. H. Sherlock, N. Sperber, BE 679271; eidem, US 3337570 (1965, 1967 both to Schering). Pharmacology: A. S. Watnick et al., Arch. Int. Pharmacodyn. 190, 78 (1971). Metabolism in humans: B. Katchen et al., J. Pharmacol. Exp. Ther. 187, 152 (1973). Clinical evaluation of analgesic activity: J. S. Finch, T. J. DeKornfeld, J. Clin. Pharmacol. 15, 371 (1971). GC determn in plasma: C. Giachetti et al., J. High Resolut. Chromatogr. 13, 789 (1990). Toxicology studies: H. Tanaka et al., Oyo Yakuri 7, 655 (1973), C.A. 80, 44091m (1974).
Properties: Crystals from isopropyl acetate, mp 233-235°. Extremely bitter taste. LD50 in male mice, rats (mg/kg): 415, 335 orally; 198, 148 i.p.; 296, 325 s.c. (Tanaka).
Melting point: mp 233-235°
Toxicity data: LD50 in male mice, rats (mg/kg): 415, 335 orally; 198, 148 i.p.; 296, 325 s.c. (Tanaka)
Derivative Type: Lysine salt
CAS Registry Number: 55837-30-4
Manufacturers' Codes: L-104
Trademarks: Clonix (Medicamenta); Deltar (Osiris); Dolalgial (Pharmainvesti); Dorixina (Roemmers)
Molecular Formula: C13H11ClN2O2.C6H14N2O2
Molecular Weight: 408.88
Percent Composition: C 55.81%, H 6.16%, Cl 8.67%, N 13.70%, O 15.65%
Therap-Cat: Analgesic.
Keywords: Analgesic (Non-Narcotic).
Clopamide Clopenthixol Cloperastine Clopidogrel Clopidol

CAS number 17737-65-4 YesY
PubChem 28718
ChemSpider 26711 N
KEGG D03555 YesY
Jmol-3D images Image 1
Molecular formula C13H11ClN2O2
Molar mass 262.69 g mol−1
Routes of
per os
Metabolism Glucuronidation via UGT2B7
Legal status


 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Clonixin is a non-steroidal anti-inflammatory drug. It also has analgesic, antipyretic, and platelet-inhibitory actions. It is used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation.