Cloprostenol

Title: Cloprostenol
CAS Registry Number: 40665-92-7
CAS Name: (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid
Molecular Formula: C22H29ClO6
Molecular Weight: 424.92
Percent Composition: C 62.18%, H 6.88%, Cl 8.34%, O 22.59%
Literature References: Aryloxymethyl analog of prostaglandin F2a, q.v. Prepn: J. Bowler, DE 2223365 (1972 to ICI), C.A. 78, 110692v (1973); D. Binder et al., Prostaglandins 6, 87 (1974). Synthesis and biological activity: eidem, ibid. 15, 773 (1978). Short synthesis: N. R. A. Beeley et al., Tetrahedron 37, Suppl. 9, 411 (1981). Disposition in the rat and marmoset: G. R. Bourne et al., Xenobiotica 9, 623 (1979). Effect on fertility in cows: N. Baishya et al., Br. Vet. J. 136, 227 (1980); on superovulation, fertilization, egg transport in ewes: D. Whyman, R. W. Moore, J. Reprod. Fertil. 60, 267 (1980).
Derivative Type: Sodium salt
CAS Registry Number: 55028-72-3
Manufacturers' Codes: ICI-80996
Trademarks: Estrumate (Mallinckrodt); Planate (Mallinckrodt)
Molecular Formula: C22H28ClNaO6
Molecular Weight: 446.90
Percent Composition: C 59.13%, H 6.32%, Cl 7.93%, Na 5.14%, O 21.48%
Therap-Cat-Vet: In treatment of infertility in sows, gilts. In synchronization of estrus.
Clopyralid Cloquintocet-Mexyl Cloranolol Clorazepic Acid Clorexolone