Clorexolone

Title: Clorexolone
CAS Registry Number: 2127-01-7
CAS Name: 6-Chloro-2-cyclohexyl-2,3-dihydro-3-oxo-1H-isoindole-5-sulfonamide
Additional Names: 6-chloro-2-cyclohexyl-3-oxo-5-isoindolinesulfonamide; 5-chloro-2-cyclohexyl-1-oxo-6-sulfamoylisoindoline; 5-chloro-2-cyclohexyl-6-sulfamoylisoindolin-1-one; 5-chloro-2-cyclohexylphthalimidine-6-sulfonamide
Manufacturers' Codes: M & B 8430; RP-12833
Trademarks: Flonatril (Specia); Nefrolan (M & B)
Molecular Formula: C14H17ClN2O3S
Molecular Weight: 328.81
Percent Composition: C 51.14%, H 5.21%, Cl 10.78%, N 8.52%, O 14.60%, S 9.75%
Literature References: Prepn: BE 620654; G. E. Lee, W. R. Wragg, US 3183243 (1963, 1965 both to May & Baker).
Properties: Prisms, mp 266-268°. Soly in water at 25°: 16 mg/l.
Melting point: mp 266-268°
Therap-Cat: Diuretic.
Keywords: Diuretic; Sulfonamide Derivatives.
Cloricromen Clorindione Clorophene Clorprenaline Clorsulon

Clorexolone
Clorexolone.png
Systematic (IUPAC) name
6-chloro-2-cyclohexyl-3-oxo-2,3-dihydro- 1H-isoindole-5-sulfonamide
Clinical data
Legal status  ?
Identifiers
CAS number 2127-01-7
ATC code C03BA12
PubChem CID 16473
ChemSpider 15615
UNII Q2PLT3FS05 YesY
KEGG D01436
Chemical data
Formula C14H17ClN2O3S 
Mol. mass 328.814 g/mol

Clorexolone is a low-ceiling sulfonamide diuretic.