Condurangin

Title: Condurangin
CAS Registry Number: 1401-98-5
Additional Names: Kondurangin
Literature References: Bitter principle from the bark of the Condurango vine, Marsdenia condurango Reichb. f., Asclepiadaceae, also known as eagle vine, mataperro, condor vine. Habit. Ecuador, Peru. Isoln: Korte, Korte, Z. Naturforsch. 10b, 223 (1955); Zechner, Zölss, Sci. Pharm. 24, 107 (1956). Separation of fractions: Cellarius, Zechner, ibid. 34, 10 (1966). Proposed structure of the aglycone, condurangogenin A: Tschesche et al., Tetrahedron 21, 1777, 1797 (1965); 23, 1461 (1967).
Properties: Crystals from dil methanol, mp 186-188°. uv max (methanol): 277 nm. Soluble in chloroform, methanol; slightly sol in water. Practically insol in ether, petr ether. Bitterness threshold 1:20,000.
Melting point: mp 186-188°
Absorption maximum: uv max (methanol): 277 nm
Therap-Cat: Astringent.
Conessine Congressane Conhydrine Coniferin Coniferyl Alcohol